Lyric discussion by MAeStROx 

OK are you guys ready? So this song is about the Dopaminergic system in our brain, used to be called the "pleasure center" - hence the line "Welcome to the pleasure dome". I'm pretty sure he didn't know about it and yet he depicted reality as it is. It is the system used to motivate us to eat, have sex, and a bunch of other stuff(all addictions sprout from this sytem).

This system acts in a way that it controls our behavior, therefore making us run like "rats in this experiment", guided towards what will cause us pleasure. This system can easily get fucked up, and not to mention the fact that every single person being driven by his animal pleasure urges, is acting like an addict completely oblivious to how fanatic he gets about things, and going through life in an addict-like self deception and denial to the enviornment.

So the set your mind to one side, might mean one ideaology, because once you embrace it you can easily go into denial about it's logical plausability, or it might also mean a certain drug or certain behavior.

This system is there to rob us of free-will so that we survive(how much is eating really supposed to be a choice?). The only problem is that human kind has found infinite ways to short-circuit it. Hey even South Park made an episode on it (Freemium Isn't Free) If you want to learn more: dopamineproject.org

An error occured.