Lyric discussion by Oedipa_Maas 

Oh god this song. "All I need is a safe place to bleed..."

It's obviously, and heartbreakingly, about drug addiction, in my opinion. And I love that he can portray the bleakness of rehab in so few lines. "Puke it up so the doctor can write me a new prescription" -- the physical discomfort of the actual treatment, "Tranquil as a dove, people that have lost their true love" -- the isolation of feeling lost and being surrounded by equally lost people.

And I agree with cheetohman. The last part is clearly:

Take me up my lord Take me up today Take me out of this place Take me up with you today.

Which could be interpreted as a plea to god for death, or could be interpreted as a plea to the "heavenly bodies above" to "take me up" (let him get high). I suspect it's meant to be both, anything to "take [him] out of this place."

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