"is not about antidepressants, but about the more general experience of facing the sources of one's depression and adjusting brain chemistry without medication: "Take Your Medicine" is literally about conjuring up the strength to face the ugly things in yourself that most of us prefer to deny exist. In the case of this song, taking one's medicine is not about popping a pharmaceutical but is more accurately about having the guts to do some not-so-fun inner psychological work. Scientific studies have shown you can alter your brain chemistry simply by choosing to practice thinking in a different way. In that sense, ‘taking your medicine' means having the discipline to break some bad mental habits and thereby changing your brain chemistry. Letting go of the inner monsters referenced in that song has helped me feel much better. But it wasn't an easy psychological process getting through that."
from an interview
"is not about antidepressants, but about the more general experience of facing the sources of one's depression and adjusting brain chemistry without medication: "Take Your Medicine" is literally about conjuring up the strength to face the ugly things in yourself that most of us prefer to deny exist. In the case of this song, taking one's medicine is not about popping a pharmaceutical but is more accurately about having the guts to do some not-so-fun inner psychological work. Scientific studies have shown you can alter your brain chemistry simply by choosing to practice thinking in a different way. In that sense, ‘taking your medicine' means having the discipline to break some bad mental habits and thereby changing your brain chemistry. Letting go of the inner monsters referenced in that song has helped me feel much better. But it wasn't an easy psychological process getting through that."