Lyric discussion by Nexus7 

I think bana had it right. Martin writes the songs, and it seems to me that this song is perfect for Dave Gahan... Remember how his habit nearly did him in? He was dead for 2 minutes. Certain lines in this song probably refer to withdrawl too.

Feel the fever coming You're shaking and twitching You can scratch all over But that won't stop you itching

@Nexus7 Yep, those are symptoms/side effects of drug withdrawal, namely heroin.

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