Lyric discussion by Prodigal 

Well...I hate to end the arguing, but heres the answer from the source itself....Mr Serj.

Found in the August 18 2001 issue of Kerrang Metal magazine, taken from the first impression of the album "Toxicity" Kerrang did with Serj and John of SoaD.

John: It's about your poisonous content. Your toxicity level. But toxicity doesn't necessarily mean the toxicity of a person, it can be the toxicity of a city. Or the toxicity of a nation. The toxicity of a speech. It's just toxicity in general or whatever.

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